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Price Schedule
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GeneXpress® Timeline and Cost for single protein |
| Service Level |
Timing |
Cost ($000s) |
| 1 Cloning &
expression |
8 to 12 weeks |
25 - 35* |
| 2 Purification/ Process Development |
2 to 4 months |
100 – 200 * |
| 3 cGMP Phase I
materials |
4 to 6 months |
350 – 750 * |
4 cGMP Phase II/III
and defined process |
TBD |
TBD |
| 5 cGMP Commercial Materials |
TBD |
TBD |
* plus modest royalties on commercialization
* technology transfer available at each stage |
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Production of Multiple Proteins for Screening Purposes |
| Number of genes/year |
1 |
5(price/protein) |
10(price/protein) |
Phase 1
Cloning and Expression1 |
$25,000 |
$100,000 (20,000) |
$175,000 (17,500) |
| Fermentation 2L2 |
$2,500 |
$10,000 (2,000) |
$17,500 (1,750) |
| His-tag or affinity purification (2L)3 |
$2,500 |
$10,000 (2,000) |
$17,500 (1,750) |
| Fermentation 10L2 |
$7,500 |
$30,000 (6,000) |
$52,500 (5,250) |
| His-tag or affinity purification (10L)3 |
$7,500 |
$30,000 (6,000) |
$52,500 (5,250) |
| Fermentation optimization (MOI; hpi; T; protease inhibitors) |
$12,500 |
$50,000 (10,000) |
$87,500 (8,750) |
| No licensing of technology required. |
1Includes production of 500 ml culture and full report describing cloning, sequence and virus bank preparation
2Fermentation is performed under standard conditions (MOI=1, Temp=28ºC, harvest time= 72 hours after infection
3No purification development included. |
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